Since 2007, the Duke Clergy Health Initiative (CHI) has identified, created, and promoted evidence-based practices to enhance the well-being of United Methodist clergy and congregations in North Carolina. In 2023, a new partnership with the Duke Religion and Social Change Lab (RaSCL), anchored by the Seminary to Early Ministry (SEM) Study, helps us resource seminarians and their communities, too. Together, we’re providing the most substantial longitudinal data sets to date on trends affecting faith leaders from seminary through retirement. Funded by The Duke Endowment, the Collaborative works closely with Duke Divinity School and the two Annual Conferences of the North Carolina United Methodist Church to translate our research findings into policies, programs, and practices that improve ministerial well-being across shifting life stages and landscapes.