Maintaining a vital connection with the Church enables the Baptist House to flourish and grow. The primary relationships of the Baptist House are with the Cooperative Baptist Fellowship (North Carolina and national) and the Baptist World Alliance. The Baptist House also relates to and partners with other Baptist groups in the United States and throughout the world. Its board of directors, faculty, and students represent memberships in a range of organizations including:
- Baptist World Alliance
- Cooperative Baptist Fellowship of North Carolina
- Cooperative Baptist Fellowship
- Alliance of Baptists
- American Baptist Churches, USA
- National Baptist Convention, USA
Baptists and Catholics attend conversation between the Baptist World Alliance (BWA) and the Catholic Church in December 2008 at Duke Divinity School.